Publications


Research Articles


High-throughput, fluorescent-aptamer-based measurements of steady-state transcription rates for the Mycobacterium tuberculosis RNA polymerase


Drake Jensen, Ana Ruiz Manzano, Maxwell Rector, Eric J Tomko, M. Thomas Record, Eric A. Galburt

Nucleic Acids Research, vol. 51(19), 2023


Mycobacterium tuberculosis DNA repair helicase UvrD1 is activated by redox-dependent dimerization via a 2B domain cysteine


Ankita Chadda, Drake Jensen, Eric J. Tomko, Ana Ruiz Manzano, Binh Nguyen, Timothy Lohman, Eric A. Galburt

Proceedings of the National Academy of Sciences, vol. 119(8), 2022


Molecular dissection of RbpA-mediated regulation of fidaxomicin sensitivity in mycobacteria


Jerome Prusa, Dennis X. Zhu, Aidan J. Flynn, Drake Jensen, Ana Ruiz Manzano, Eric A. Galburt, Christina L. Stallings

Journal of Biological Chemistry, vol. 298(4), 2022


CarD and RbpA modify the kinetics of initial transcription and slow promoter escape of the Mycobacterium tuberculosis RNA polymerase


Drake Jensen, Ana Ruiz Manzano, Jayan Rammohan, Christina L Stallings, Eric A Galburt

Nucleic Acids Research, vol. 47(13), 2019, pp. 6685-6698


Domains within RbpA Serve Specific Functional Roles That Regulate the Expression of Distinct Mycobacterial Gene Subsets


Jerome Prusa, Drake Jensen, Gustavo Santiago-Collazo, Steven S. Pope, Ashley L. Garner, Justin J. Miller, Ana Ruiz Manzano, Eric A. Galburt, Christina L. Stallings

Journal of Bacteriology, vol. 200(13), 2018


Effects of increasing the affinity of CarD for RNA polymerase on Mycobacterium tuberculosis growth, rRNA transcription, and virulence


Ashley L. Garner, Jayan Rammohan, Jeremy P. Huynh, Lucas M. Onder, James Chen, Brian Bae, Drake Jensen, Leslie A. Weiss, Ana Ruiz Manzano, Seth A. Darst, Elizabeth A. Campbell, Bryce E. Nickels, Eric A. Galburt, Christina L. Stallings

Journal of Bacteriology, vol. 199(4), 2017


The exchanged EF-hands in calmodulin and troponin C chimeras impair the Ca2+-induced hydrophobicity and alter the interaction with Orai1: a spectroscopic, thermodynamic and kinetic study


Drake Jensen, Nicole Reynolds, Ya Ping Yang, Shubha Shakya, Zhi Qiang Wang, Dennis J. Stuehr, Chin Chuan Wei

BMC Biochemistry, vol. 16(1), 2015


Book Chapters & Reviews


Calcium | Calcium Signaling: NO Synthase


Zhi-Qiang Wang, Dennis J. Stuehr, Chin-Chuan Wei, Drake Jensen

Joseph Jez, Encyclopedia of Biological Chemistry III, Third Edition, Elsevier, Oxford, 2021, pp. 602-608


Teaching Protocols


Isothermal Titration Calorimetry and Macromolecular Visualization for the Interaction of Lysozyme and Its Inhibitors


Chin-Chuan Wei, Drake Jensen, Tiffany Boyle, Leah C. O'Brien, Cristina De Meo, Nahid Shabestary, Douglas J. Eder

Journal of Chemical Education, vol. 92(9), 2015, pp. 1552-1556


M2+•EDTA Binding Affinities: A Modern Experiment in Thermodynamics for the Physical Chemistry Laboratory


Leah C. O'Brien, Hannah B. Root, Chin-Chuan Wei, Drake Jensen, Nahid Shabestary, Cristina De Meo, Douglas J. Eder

Journal of Chemical Education, vol. 92(9), 2015, pp. 1547-1551


Theses


Fluorescent-based Approaches for Quantifying Bacterial Transcription Initiation Kinetics


Drake Jensen

Washington University in Saint Louis, 2023 Apr 4


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